A 28-year-old woman in the ICU with ARDS has been sedated with propofol 60 mcg/kg/min for 96 hours. She develops metabolic acidosis (pH 7.18, lactate 6.2 mmol/L), bradycardia with ST elevations, creatine kinase 45,000 U/L, and triglycerides 8.4 mmol/L (743 mg/dL). After discontinuing propofol, which intervention most directly addresses the underlying pathophysiology?
A
Continuous renal replacement therapy
B
Dantrolene 2.5 mg/kg
C
Sodium bicarbonate infusion
D
L-carnitine supplementation
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